How are malignant phyllodes tumors treated?
Local therapy for a phyllodes tumor will include surgery (wide excision or mastectomy) to remove the tumor and extra tissue around it. Sometimes, radiation is given as well. Systemic therapy (chemotherapy) may be used if a malignant phyllodes tumor has spread outside of the breast, though this not common.
Is malignant phyllodes tumor curable?
Whether phyllodes tumors are benign, borderline, or malignant, the treatment is the same: surgery to remove the tumor, along with at least 1 centimeter of surrounding healthy breast tissue. Some doctors feel that an even wider margin of healthy tissue should be removed.
What percentage of phyllodes tumors are malignant?
Reports have suggested, however, that about 85-90% of phyllodes tumors are benign and that approximately 10-15% are malignant. Although benign phyllodes tumors do not metastasize, they have a tendency to grow aggressively and can recur locally. Like other sarcomas, malignant phyllodes tumors metastasize hematogenously.
Can borderline phyllodes tumors come back malignant?
Sometimes, phyllodes tumours can come back in the same area of breast tissue (known as a local recurrence). This risk is higher with malignant tumours. If this does happen, your surgeon may advise that you have further surgery. This may involve another wide local excision to remove the tumour.
Is phyllodes tumor benign or malignant?
Phyllodes tumors are often divided into 3 groups, based on how they look under a microscope: Benign (non-cancerous) tumors account for more than half of all phyllodes tumors. These tumors are the least likely to grow quickly or to spread.
What causes malignant phyllodes tumor?
Phyllodes Tumor Causes and Risk Factors Experts don’t know what causes phyllodes tumors. Women who have a rare genetic disease called Li-Fraumeni syndrome are more likely to have them. They rarely affect men. Women of any age can get phyllodes tumors, but they’re most common in your 40s.
Are phyllodes tumor painful?
Signs and symptoms of phyllodes tumors The lump is usually not painful. If left unchecked, the lump can create a visible bulge as it pushes against the skin. In more advanced cases — whether benign, borderline, or malignant — a phyllodes tumor can cause an ulcer or open wound to form on the breast skin.
Can Phyllodes spread?
Phyllodes tumors tend to grow quickly, but they rarely spread outside the breast. Although most phyllodes tumors are benign (not cancerous), some are malignant (cancerous) and some are borderline (in between noncancerous and cancerous).
Can phyllodes tumor be misdiagnosed?
It has been suggested that phyllodes tumors may be misdiagnosed as fibroadenomas by core biopsy. However, in this case, pathology supports correct initial diagnosis of fibroadenoma and demonstrates a portion of the original fibroadenoma along the periphery of the malignant phyllodes tumor.
Is a 2 cm breast tumor big?
In general, stage IIB describes invasive breast cancer in which: the tumor is larger than 2 cm but no larger than 5 centimeters; small groups of breast cancer cells — larger than 0.2 mm but not larger than 2 mm — are found in the lymph nodes or.
What is the life expectancy of someone with phyllodes tumor?
The vast majority of phyllodes tumors occur in women, with a median age of presentation of 42 to 45 years (range 10 to 82 years) [ 3,6-8 ]. Higher-grade tumors are more common in older patients [ 9 ]. In men, phyllodes tumors usually occur in association with gynecomastia [ 3 ].
Can phyllodes tumor be caused by meth use?
The cause of phyllodes tumors is unknown. They may just arise as people age. Several factors may be involved in causing these tumors to grow, including: Phyllodes tumors grow very quickly. The first sign is often a lump under your skin. The lump will feel smooth to the touch.
Is surgery the only treatment for pituitary tumour?
Surgery is the most common treatment for pituitary tumors. If the pituitary tumor is benign and in a part of the brain where neurosurgeons can safely completely remove it, surgery might be the only treatment needed. The patient will probably need surgery if the tumor: Is producing hormones that medication cannot control.
Do benign tumors need chemotherapy?
Benign tumors do not spread, so after-surgery treatments do not include chemotherapy or radiation. All tumors removed during surgery will be sent for pathology, regardless of whether the surgeon believes the mass is a benign tumor or malignant.