How do you treat pediatric ITP?

How is ITP treated in a child?

Corticosteroids. Brief treatment with steroid medication helps prevent bleeding by decreasing platelet destruction.
Intravenous immune globulin (IVIg). A single dose of IVIg to slow the destruction of platelets.
Anti-D or Rh immune globulin.

How is chronic ITP treated in children?

However, 20-30% of affected children may develop chronic ITP (lasting for more than 12 months). First line treatment includes intravenous immunoglobulin (IVIG), corticosteroids or anti-D immunoglobulin. Second line treatment includes splenectomy, immunosuppressive therapy or Rituximab.

Is ITP in children serious?

The majority of children with ITP have a low platelet count but do not have dangerous bleeding. If severe bleeding is not present at the time of diagnosis then it is very rare for dangerous bleeding to develop later.

What is normal platelet count for child?

In healthy pediatric subjects normal count platelet ranges between 250,000 μL and 450,000 μL.

When should you give ITP platelets?

Therefore, current American Society of Hematology guidelines recommend that platelet transfusion in ITP patients be reserved for those with catastrophic hemorrhage or having concurrent surgery.

Do children outgrow ITP?

Adults have this form more often than children, but it does affect adolescents. Females are two to three times as likely as males to contract this form of the disease. Chronic ITP can recur often and requires continual follow-up care with a blood specialist (hematologist).

Can ITP turn into leukemia?

ITP does not turn into a more serious blood disorder, like leukemia or aplastic anemia. It is usually not a sign that their child will later develop other autoimmune conditions, such as systemic lupus erythematosus (SLE or “lupus”).

Can ITP go away in children?

Platelet counts may go up and down for many months. Childhood ITP usually resolves itself within 12 months.

What is a high platelet count in 1 year old?

One definition considers a count from 450–700×109/L as mild thrombocytosis, 700–900×109/L as moderate, and more than 900×109/L as severe. 1.

Is 162 a low platelet count?

A low platelet count is below 150,000 (150 × 109/L). If your platelet count is below 50,000 (50 × 109/L), your risk for bleeding is higher. Even every day activities can cause bleeding. A lower-than-normal platelet count is called thrombocytopenia.

What is the optimal treatment of ITP?

Corticosteroids. Corticosteroids have been used as a first-line treatment for ITP for more than 30 years,according to available research from 2016.

Thrombopoietin receptor antagonists.

Antibody therapy.

Immunoglobulin infusions.

Avoiding certain medications and supplements.

Splenectomy.

Antibiotics.

Lifestyle changes.

How do you treat ITP?

Medications. Your doctor will talk with you about over-the-counter medications or supplements you take and whether you need to stop using any that might inhibit platelet function.

Surgery. If your condition is severe or persists despite initial drug treatment,your doctor may suggest surgery to remove your spleen.

Emergency treatment.

What is chronic ITP in children?

ITP is a blood disorder with decreased blood platelets,which may result in easy bruising,bleeding gums,and internal bleeding.

The cause is usually unknown,but it may be an autoimmune disorder or follow a viral illness. It can also occur with certain medicines or vaccines.

Treatment may not be needed. Observation alone is a very common approach.

Does ITP patient need surgery?

Idiopathic thrombocytopenic purpura (ITP) is characterized by a low platelet count that is the result of both immune-mediated platelet destruction and suppression of platelet production. 1,2 In patients with ITP undergoing surgery, bleeding associated with a low preoperative platelet count can lead to unsuccessful outcome.