Is cidex harmful?
Emergency overview: May cause eye, skin and respiratory irritation. May elicit an allergic reaction. CIDEX OPA Solution has been reported to cause anaphylactic-like reactions in bladder cancer patients undergoing repeated cystoscopy. Repeated exposure may cause skin dryness or cracking.
What is Ortho-Phthalaldehyde used for?
Ortho-Phthalaldehyde (OPA) has been approved for high-level sterilization of heat-sensitive medical instruments and is increasingly being used as a replacement in the healthcare industry for glutaraldehyde, a known sensitizer.
What is the unique characteristic of an ortho-Phthalaldehyde?
OPA has several potential advantages compared with glutaraldehyde. It has excellent stability over a wide pH range (pH 3 to 9), is not a known irritant to the eyes and nasal passages, does not require exposure monitoring, has a barely perceptible odor, and requires no activation.
Is OPA toxic?
The toxicological properties of CIDEX OPA Solution have been studied extensively. Results demonstrate that the solution is safe when used as directed. A summary of results from the toxicity tests performed appears below.
Does glutaraldehyde produce toxic fumes?
Glutaraldehyde itself does not burn. POISONOUS GASES ARE PRODUCED IN FIRE. Use water spray to keep fire-exposed containers cool.
Is glutaraldehyde banned in Europe?
According to the harmonised classification and labelling (ATP09) approved by the European Union, this substance is fatal if inhaled, is toxic if swallowed, causes severe skin burns and eye damage, is very toxic to aquatic life, is toxic to aquatic life with long lasting effects, may cause an allergic skin reaction, may …
Does cidex OPA need ventilation?
CIDEX disinfectant is often preferred since it is virtually odorless. CIDEX does not require any special ventilation since it does not cause irritation to the eyes or nasal passages, but it is best to use in a well-ventilated area. Avoid contact with eyes, skin, and clothing.
Is glutaraldehyde effective against viruses?
Several investigators showed that ≥2% aqueous solutions of glutaraldehyde, buffered to pH 7.5–8.5 with sodium bicarbonate effectively killed vegetative bacteria in <2 minutes; M. tuberculosis, fungi, and viruses in <10 minutes; and spores of Bacillus and Clostridium species in 3 hours 542, 592-597.
What chemical is OPA?
Phthalaldehyde
Phthalaldehyde (sometimes also o-phthalaldehyde or ortho-phthalaldehyde, OPA) is the chemical compound with the formula C6H4(CHO)2. It is one of three isomers of benzene dicarbaldehyde, related to phthalic acid.
Is cidex flammable?
Emergency overview: Flammable. Properties affecting health: Toxic if swallowed. Irritating to eyes, skin and respiratory tract.
Does cidex Opa need ventilation?
Does glutaraldehyde sterilize?
Glutaraldehyde is used as a cold sterilant to disinfect and clean heat-sensitive equipment such as dialysis instruments, surgical instruments, suction bottles, bronchoscopes, endoscopes, and ear, nose, and throat instruments.
Is ortho-phthalaldehyde hazardous to aquatic environment?
Hazardous to the aquatic environment (Long-term) – Category 1 Hazardous to the ozone layer – Category 1 Combustible. Recently, the use of ortho-phthalaldehyde (OPA) has been increasing as an alternative to glutaraldehyde (GA)for endoscope disinfection.
What is o-phthalaldehyde used for?
USE: o-Phthalaldehyde is used as a disinfectant, mainly for dental and medical equipment. EXPOSURE: Workers that produce or use o-phthalaldehyde may have direct skin contact. The general population may be exposed by contact with residual disinfectant.
How many workers are exposed to o-phthalaldehyde in the US?
NIOSH (NOES Survey 1981-1983) has statistically estimated that 3253 workers (2222 of these are female) were potentially exposed to o-phthalaldehyde in the US (1). Occupational exposure to o-phthalaldehyde may occur through dermal contact with this compound at workplaces where o-phthalaldehyde is produced or used (SRC).
Can ortho-phthalaldehyde disinfectants cause upper aerodigestive complications?
We report an unusual, but severe, upper aerodigestive complication from the use of ortho-phthalaldehyde solution, a commonly used endoscope disinfectant. /CASE REPORTS/ PURPOSE: Ortho-phthalaldehyde ( Cidex OPA) is a commonly used solution for rapid sterilization of flexible endoscopic equipment.