What are anti-gastric parietal cell antibodies?
Anti-gastric parietal cell antibodies are also found in 60% of atrophic gastric and 22% of gastric ulceration cases without detectable anaemia because these conditions occur well before the onset of pernicious anaemia.Anti-gastric antibodies are also found in:
What is the function of parietal cells?
Parietal cells are specialized cells in the stomach that make acid to help in food digestion and also make intrinsic factor. Intrinsic factor is required for the absorption of vitamin B12 from food.
What is parietal cell antibody (GPA)?
Also known as Parietal Cell Antibody, Gastric Parietal Cell Antibody, Anti-parietal Cell Antibody, Anti-GPA, AGPA, APCA, IgG. The parietal cells are cells that line up the wall of our stomach. They specialize in producing Intrinsic Factor and creating acid to help with food digestion.
What are parietal cell antibodies in pernicious anemia?
Additional information related to the test. Most patients with pernicious anemia have parietal cell antibodies. However, the fact that such antibodies are found with increased frequency in unaffected family members, as well as in patients with other autoimmune diseases, suggests these antibodies do not cause disease by themselves.
What are gastric parietal cells?
Alternative name: Description: Antibodies to gastric parietal cells are associated with auitoimmune gastritis and pernicious anaemia. The parietal cells of the stomach secrete intrinsic factor, which is necessary for the absorption of vitamin B12, essential for erythropoiesis.
What is antiparietal cell antibody test?
An antiparietal cell antibody test is a blood test that looks for antibodies against the parietal cells of the stomach. The parietal cells make and release a substance that the body needs to absorb vitamin B12. A blood sample is needed.