What causes a phyllodes tumor?

What causes a phyllodes tumor?

Experts don’t know what causes phyllodes tumors. Women who have a rare genetic disease called Li-Fraumeni syndrome are more likely to have them. They rarely affect men. Women of any age can get phyllodes tumors, but they’re most common in your 40s.

What are the features of the phyllodes tumor of mammary gland?

Phyllodes tumor on mammography. It shows well circumscribed oval or lobulated mass with rounded borders. A radiolucent halo may be seen around the lesion due to compression of the surroundings. Coarse calcification (but malignant microcalcification is rare) may be present.

How can you tell if a tumor is phyllodes?

Phyllodes tumors grow very quickly. Breastcancer.org says that the first symptom is often a lump under your skin. The lump will feel smooth to the touch. The skin over your breast might also turn red or discolored and feel warm.

What is the difference between phyllodes and fibroadenoma?

Fibroadenomas grow up to 2-3 cm and then stop growing but phyllodes tumors grow continually and sometimes are to 40 cm big. Both these lesions have two components, epithelial and stromal. Clinically fibroadenomas are well circumscibed, hard, oval, movable lesions.

What are phyllodes?

Phyllodes (fil-oy-deez) tumors are a rare form of breast tumor; they can be benign (not cancerous), malignant (cancerous), or borderline (having characteristics of both). Phyllodes tumors account for fewer than 1% of all breast cancers.

Can phyllodes spread?

Phyllodes tumors tend to grow quickly, but they rarely spread outside the breast. Although most phyllodes tumors are benign (not cancerous), some are malignant (cancerous) and some are borderline (in between noncancerous and cancerous).

What are Phyllodes?

How common are phyllodes tumors?

Phyllodes tumors of the breast are rare, accounting for less than 1% of all breast tumors. The name “phyllodes,” which is taken from the Greek language and means “leaflike,” refers to that fact that the tumor cells grow in a leaflike pattern. Other names for these tumors are phylloides tumor and cystosarcoma phyllodes.

Can a fibroadenoma turn into a phyllodes tumor?

The transformation of a benign fibroadenoma into a phyllodes tumor is uncommon and unpredictable. We report the case of a 40-year-old woman with a core biopsy proven fibroadenoma that underwent transformation into a malignant phyllodes tumor after 3 years of size stability.

Can a benign phyllodes tumor become malignant?

Most phyllodes tumors are benign, but in rare cases they can be malignant (cancerous). In addition, their behavior is unpredictable. In rare cases, a benign tumor can recur (grow back) as a cancer. So they’re a little different from the other benign breast conditions linked to a slight increase in breast cancer risk.

What is a Phyllode give one example?

Phyllode is a modified petiole or shoots connecting stem and leaf. Examples of Phyllode include Acacia.

Should phyllodes tumor be removed?

Most phyllodes tumors are benign. They may look very much like common benign breast tumors called fibroadenomas. Often, the pathologist needs to look at the whole tumor under the microscope to make a diagnosis. This is why surgery to remove a phyllodes tumor is recommended, even if it is thought to be benign.

What is the life expectancy of someone with phyllodes tumor?

The vast majority of phyllodes tumors occur in women, with a median age of presentation of 42 to 45 years (range 10 to 82 years) [ 3,6-8 ]. Higher-grade tumors are more common in older patients [ 9 ]. In men, phyllodes tumors usually occur in association with gynecomastia [ 3 ].

What does phyllodes tumor look like?

On a mammogram, a phyllodes tumor appears as a large round or oval mass with well-defined edges. Sometimes the tumor might look like it has rounded lobes inside it. Calcifications can show up as well. Calcifications are tiny flecks of calcium — like grains of salt — in the soft tissue of the breast.

What does phyllodes tumor mean?

Phyllodes tumors are a rare type of breast tumor. The pattern of their cells resembles leaves, and the name “phyllodes” comes from the Greek word meaning “leaf-like.” Phyllodes tumors can grow quickly, but they do not always spread beyond the breast.

How do phyllodes tumors develop in the breast?

How Phyllodes Tumors Develop in the Breast

  • Symptoms and Diagnosis of Phyllodes Tumors of the Breast
  • Treatment of Phyllodes Tumors of the Breast
  • Follow-Up Care for Phyllodes Tumors of the Breast