What do the cells in the trophoblast differentiate into?
Trophoblasts as a specific cell lineage are crucial for the correct function of the placenta. Human trophoblast stem cells (hTSCs) are a proliferative population that can differentiate into syncytiotrophoblasts and extravillous cytotrophoblasts.
What are 2 ways that stem cells are differentiated?
Stem cells can be categorized into groups depending on their ability to differentiate.
- Totipotent: can differentiate into all cell types;
- Pluripotent: can differentiate into almost all cell types;
- Multipotent: can differentiate into a related family of cell types;
Are trophoblast cells stem cells?
These apparently immortal stem cells in culture are termed trophoblast stem (TS) cells, and exhibit the potential to differentiate into multiple trophoblastic cell types in vitro, as well as in vivo.
What are trophoblast stem cells?
Trophoblast stem cells (TSC) are the precursors of the differentiated cells of the placenta. In the mouse, TSC can be derived from outgrowths of either blastocyst polar trophectoderm (TE) or extraembryonic ectoderm (ExE), which originates from polar TE after implantation.
What are the cells of Rauber?
‘Cells of Rauber’ are trophoblast cells that are in contact with the inner mass of blastocyst. They are in contact with embryos and when the developing embryo reaches the uterine cavity after five to six days of fertilization, it is called blastocyst. A blastocyst is usually made up of a hundred cells.
What is the role of trophoblast in the germinal stage?
They provide nutrients to the embryo and develop into a large part of the placenta. They form during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg to become extraembryonic structures and do not directly contribute to the embryo….
Which type of stem cell can differentiate into the most types of cells?
Embryonic stem cells. These embryonic stem cells are pluripotent. This means that they can turn into more than one type of cell.
What causes stem cells to differentiate into different types of cells?
Stem cells produce new cells by dividing. In the right conditions, these new cells can then continue to divide and differentiate into specialized cells. Stem cells can also divide to produce new stem cells to replace themselves. They can divide and develop into cells of other types, to a greater or lesser degree.
What is the main function of trophoblast?
Trophoblasts are cells that form the outer layer of a blastocyst, which provides nutrients to the embryo, and then develop into a large part of the placenta.
Are trophoblast cells totipotent?
These cells are called totipotent and have the ability to develop into a new organism. The blastocyst has an outer-layer of cells called the trophoblast, which will eventually form the protective placenta. Inside the trophoblast is a group of cells called the inner cell mass.
Are trophoblast cells multipotent?
These cells are self-renewing, clonogenic, and multipotent with the ability to differentiate into cells of three germ layers in vitro and in vivo.
Where are cells of Rauber present?
Cells of Rauber are found in the trophoblast cells in contact with the inner cell mass of the blastocyst. Blastocyst contains blastomeres which are arranged into an outer layer called the trophoblast.