What does AJCC stage mean?
A system to describe the amount and spread of cancer in a patient’s body, using TNM. T describes the size of the tumor and any spread of cancer into nearby tissue; N describes spread of cancer to nearby lymph nodes; and M describes metastasis (spread of cancer to other parts of the body).
Who is responsible for AJCC TNM staging?
The American Joint Committee on Cancer (AJCC) is responsible for the staging criteria for all cancers. For the past 20 years, the AJCC cancer staging manual has grouped all nonmelanoma skin cancers, including cSCC, together for the purposes of staging.
What is advanced stage HCC?
Advanced HCC was defined as a liver tumor not eligible for local therapies given the extent of disease or liver tumors that recurred after local therapies. Intrahepatic recurrence after local treatment was considered metastatic disease.
What is AJCC 8th edition?
The Eighth Edition of the AJCC Cancer Staging Manual, published in October 2016, is a compendium of all currently available information on the staging of adult cancers for all clinically important anatomic sites.
What does the grade of a tumor mean?
Tumor grade is the description of a tumor based on how abnormal the tumor cells and the tumor tissue look under a microscope. It is an indicator of how quickly a tumor is likely to grow and spread.
How do you reference AJCC 8th edition?
Amin MB, Edge S, Greene F, Byrd DR, Brookland RK, Washington MK, Gershenwald JE, Compton CC, Hess KR, et al. (Eds.). AJCC Cancer Staging Manual (8th edition). Springer International Publishing: American Joint Commission on Cancer; 2017 [cited 2016 Dec 28].
What does stage pt1a melanoma mean?
Stage 1A. Stage 1A means the: melanoma is less than 1 mm thick. outer layer of skin (epidermis) covering the tumour may or may not look broken under the microscope (ulcerated or not ulcerated)
Is the AJCC 7th edition a useful staging system for hepatocellular carcinoma?
Background/aims: In 2009, the American Joint Committee on Cancer (AJCC) published the 7th edition of the hepatocellular carcinoma (HCC) staging system. We investigated the prognostic value of the 7th AJCC staging system as a clinical staging system in patients with HCC.
When will the 8th edition of the AJCC staging manual be available?
Accessed January 30th, 2022. AJCC 7th edition staging was sunset on December 31, 2017; as of January 1, 2018, use of the 8th edition is mandatory ( Amin: AJCC Cancer Staging Manual, 8th Edition, 2018 )
Is the 7th AJCC staging system better than the BCLC system?
The 7th AJCC staging system provided better prognostic power than the 6th for patients with HCC, but not better than that of the BCLC system. Thus, the 7th AJCC staging system should be applied cautiously in patients with advanced HCC because of its low prognostic power in advanced stages.
What percentage of AJCC 7th edition patients are evenly distributed across stages?
These patients were evenly distributed between AJCC 7th edition stages (stage I, 28%; stage II, 32%; stage III, 35%), which was not the case for the other systems.