What drugs are dihydropyridine calcium channel blockers?
Generic and brand names of dihydropyridine calcium channel blockers drugs include:
- Aliskiren/amlodipine (Amturnide, Tekamlo)
- Aliskiren/amlodipine/hydrochlorothiazide.
- Amlodipine (Katerzia, Norvasc)
- Amlodipine/atorvastatin (Caduet)
- Benazepril/amlodipine (Lotrel)
- Clevidipine (Cleviprex)
Is amlodipine a non dihydropyridine?
Dihydropyridines — The dihydropyridines, including nifedipine, isradipine, felodipine, nicardipine, nisoldipine, lacidipine, amlodipine, and levamlodipine are potent vasodilators that have little or no negative effect clinically upon cardiac contractility or conduction.
What is Nondihydropyridine and dihydropyridine?
Dihydropyridine CCBs (nifedipine and amlodipine) primarily act on vascular smooth muscles. Nondihydropyridine CCBs (verapamil > diltiazem) primarily act on the heart.
What are examples of non-dihydropyridine calcium channel blockers?
Calcium Channel Blockers, Non-dihydropyridine
- Calan.
- Calan SR.
- Cardizem.
- Cardizem CD.
- Cardizem LA.
- Cartia XT.
- Covera HS.
- Dilacor.
Which B blockers are Cardioselective?
The cardio-selective beta-1-blockers include atenolol, betaxolol, bisoprolol, esmolol, acebutolol, metoprolol, and nebivolol.
What is the difference between dihydropyridine and Nondihydropyridine?
Dihydropyridine (DHP) CCBs tend to be more potent vasodilators than non-dihydropyridine (non-DHP) agents, whereas the latter have more marked negative inotropic effects.
What is the difference in dihydropyridine and non dihydropyridine calcium channel blockers what conditions are they used to treat?
The dihydropyridines are more vascular selective and the non-dihydropyridines are more myocardial selective and tend to reduce the heart rate. Further important differences are between short- and long-acting forms of the calcium channel antagonists.
What is an example of dihydropyridine?
Figure 1: Example of a few dihydropyridine-containing antihypertensive commercial drugs. Calcium channels are part of plasma membrane proteins that are made up of calcium selective pores that are opened by a change in the voltage of the membrane.
What is dihydropyridine L-type calcium channel blocker?
A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. A dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable.
What is the mechanism of action of dihydropyridine?
Many commercial drugs have been derived from dihydropyridine due to its antihypertensive property. Dihydropyridine derivatives work by acting as calcium channel blockers blocking the intake of calcium ions into the vascular smooth muscle and, to a lesser extent, cardiac muscles.
What drugs are dihydrophyridine Class L blockers?
Dihydropyridine class L -type calcium channel blockers include, in alphabetical order (brand names vary in different countries): The pharmaceutical drug finerenone is also a dihydrophyridine derivative, but does not act as a calcium channel blocker but as an antimineralocorticoid .