What is buspirone?

What is buspirone?

Buspirone is in a class of medications called anxiolytics. It works by changing the amounts of certain natural substances in the brain. How should this medicine be used? Buspirone comes as a tablet to take by mouth.

Can buspirone hydrochloride tablets be given to patients with hepatic or renal impairment?

Therefore, the administration of Buspirone hydrochloride tablets to patients with severe hepatic or renal impairment cannot be recommended (see CLINICAL PHARMACOLOGY ).

How should I take buspirone?

Take buspirone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Your doctor may start you on a low dose of buspirone and gradually increase your dose, not more often than once every 2 to 3 days.

What are the ingredients in buspirone hydrochloride?

Buspirone hydrochloride tablets, USP contain the following inactive ingredients: anhydrous lactose, colloidal silicon dioxide, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate. The mechanism of action of Buspirone is unknown.

¿Qué es buspirone? Buspirone se usa para el tratamiento de síntomas de la ansiedad, como miedo, tensión, irritabilidad, mareo, latido cardíaco fuerte, y otros síntomas físicos. Buspirone no es un medicamento antipsicótico y no se debe usar como substituto de una medicina recetada por su médico para el tratamiento de enfermedades mentales.

How do I take buspirone?

The leaflet will give you more information about buspirone and a full list of side-effects which you may experience from taking it. Take buspirone tablets exactly as your doctor tells you to. It is likely that you will be prescribed one 5 mg tablet to take two or three times a day to begin with. This may be increased after a few days if needed.

What is the mechanism of action of Buspar?

1 College of Pharmacy, University of Texas at Austin. Buspirone (Buspar) is a azaspirodecanedione anxiolytic agent. Its mechanism of action is extremely complex, but current investigations indicate that its main neuropharmacologic effects are mediated by the 5-HT1A receptors.

Does buspirone interact with other neuroreceptors?

Other neuroreceptor systems could be involved, as buspirone displays some affinity for DA2 autoreceptors and 5-HT2 receptors. It has been proposed that inhibition of synthesis and release of serotonin result through the combined interactions of neuroreceptors and secondary messenger systems.

Do not take this medicine in larger or smaller amounts or for longer than recommended. You may take buspirone with or without food but take it the same way each time. Some buspirone tablets are scored so you can break the tablet into 2 or 3 pieces in order to take a smaller amount of the medicine at each dose.

What is the molecular weight of buspirone hydrochloride?

Buspirone hydrochloride is a white crystalline, water soluble compound with a molecular weight of 422.0. Chemically, Buspirone hydrochloride is 8- [4- [4- (2-pyrimidinyl)-1­ piperazinyl]butyl]-8-azaspiro [4.5]decane-7,9-dione monohydrochloride. The empirical formula C 21 H 31 N 5 O 2 • HCl is represented by the following structural formula:

What happens if you are allergic to buspirone?

Buspirone side effects Get emergency medical help if you have any signs of an allergic reaction to buspirone: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: