What is considered a high level of AFP?

What is considered a high level of AFP?

AFP is measured in nanograms per milliliter (ng/mL). An AFP level between 10 ng/mL to 20 ng/mL is normal for adults. An extremely high level of AFP in your blood—greater than 400 ng/mL—could be a sign of liver tumors.

What is a good AFP level in pregnancy?


Men and nonpregnant women: 0–40 nanograms per milliliter (ng/mL) or micrograms per liter (mcg/L) footnote 2
Women 15–18 weeks pregnant: 10-150 ng/mL or mcg/L footnote 3

What is the alpha-fetoprotein test for?

What is it used for? An AFP blood test is used to check a developing fetus for risk of birth defects and genetic disorders, such as neural tube defects or Down syndrome.

What does a positive AFP test mean?

A positive AFP PLUS test means that you are in a higher likelihood group for having a baby with a neural tube defect or a chromosome abnormality. However, it does not prove by itself that there is anything wrong with the pregnancy.

What is a normal AFP level at 17 weeks?

Table II.

AFP, ng/ml Free-β-hCG, mIU/ml
Gestational ages weeks Twin Twin
16 107.4 74,046
17 109.3 60,164
18 102.4 59,711

What causes high AFP in pregnancy?

Causes of elevated AFP are: Neural Tube Defects: Neural tube defects include both spina bifida (improper closure of the fetal spine) and anencephaly (improper closure of the fetal skull). Individuals with spina bifida can have variable problems as a result of the birth defect.

What happens if AFP is high?

What do the results mean? If your results show high levels of AFP, it may confirm a diagnosis of liver cancer, or cancer of the ovaries or testicles. Sometimes, high levels of AFP can be a sign of other cancers, including Hodgkin disease and lymphoma, or noncancerous liver disorders.

What is a high tumor marker number?

Normal range: < 2.5 ng/ml. Normal range may vary somewhat depending on the brand of assay used. Levels > 10 ng/ml suggest extensive disease and levels > 20 ng/ml suggest metastatic disease.

What is an abnormal AFP level in pregnancy?

A positive test with a high AFP suggests a birth defect like spina bifida. That’s typically a result of 2.5 times or more than the “average” level of AFP you’d expect to see at that point in your pregnancy. A positive test with low AFP could mean a problem like Down syndrome or Edwards syndrome.

What is normal AFP MoM in pregnancy?

MS-AFP and AF-AFP were given as multiples of the median (MoM). Values < or = 1-2.0 MoM were considered normal. Elevated levels were defined to be greater than 2 MoM.

What causes elevated alpha fetoprotein?

High levels of AFP can be a sign of liver cancer or cancer of the ovaries or testicles, as well as noncancerous liver diseases such as cirrhosis and hepatitis.

What is AFP test for liver in adults?

AFP (Alfa-fetoprotein) Hepatitis C for Patients AFP is a protein that is present in patients with liver disease. AFP is also a “tumor marker” and may be used to see if a patient has liver cancer. (Liver cancer is also called hepatocellular carcinoma).