What is the best medicine for malaria?
Medications
- Chloroquine phosphate. Chloroquine is the preferred treatment for any parasite that is sensitive to the drug.
- Artemisinin-based combination therapies (ACTs). ACT is a combination of two or more drugs that work against the malaria parasite in different ways.
What is the synthetic drug to cure malaria?
chloroquine, synthetic drug used in the treatment of malaria. Chloroquine, discovered in 1934 and introduced into medicine in the 1940s, is a member of an important series of chemically related antimalarial agents, the quinoline derivatives. Chloroquine is administered orally as chloroquine phosphate.
What was the first antimalarial drug?
Since the isolation in 1820 of quinine, the first chemically purified effective treatment for malaria, a number of other natural and synthetic compounds have been developed (Fig. 1). However, as time passed, strains of the parasite began to show signs of resistance towards these drugs, rendering them less effective.
What is the best injection for malaria?
Severe malaria should be treated with intravenous (IV) antimalarial medications. IV artesunate is the first-line drug for treatment of severe malaria in the United States. Artesunate for InjectionTM was approved by the FDA and is commercially available in the United States.
What is chloroquine made of?
Chloroquine, 7-chloro-4-(4-diethylamino-1-methylbutylamino)-quinoline (37.1. 3), is made by reacting 4,7-dichloroquinoline (37.1. 1.1) with 4-diethylamino-1-methylbutylamine (37.1.
What plant does chloroquine come from?
The drug has a long track record in medicine, having been used since the 1940s as an antimalarial. The modern drug is a synthetic form of quinine, which is found in the bark of the Cinchona plant. The plant was taken as an herbal remedy by indigenous Peruvians four centuries ago to treat fever.
Is Artemisinin the same as chloroquine?
Artemisinin combination therapy (ACT) is recommended as first-line treatment for uncomplicated Plasmodium falciparum malaria, whereas chloroquine is still commonly used for the treatment of non-falciparum species (Plasmodium vivax, Plasmodium ovale and Plasmodium malariae).
What plant is chloroquine made from?
The cinchona tree is native to Peru. Quinine was the treatment of choice until the 1940s when other drugs, with fewer side effects, replaced it. One of those drugs was chloroquine, which was discovered in 1934.
Is chloroquine good for malaria?
Chloroquine can be prescribed for either prevention or treatment of malaria. This fact sheet provides information about its use for the prevention of malaria infection associated with travel. Who can take chloroquine? Chloroquine can be prescribed to adults and children of all ages.