What is the difference between microemulsion and nanoemulsion?
The only distinctive difference that separates a nanoemulsion from a microemulsion is their thermodynamic stability, i.e., a microemulsion is thermodynamically stable while a nanoemulsion is not.
Why are nanoemulsions stable?
The small droplet size of nanoemulsions provides stability against sedimentation or creaming because of the Brownian motion and consequently the diffusion rate are higher than the sedimentation rate induced by the gravity force.
What is microemulsion Slideshare?
Microemulsion is an isotropic mixture of oil, surfactant, Cosurfactant and drug. Upon mild agitation followed by dilution in aqueous media, such as gastrointestinal (GI) fluids, the systems can form fine oil in water (O/W) Microemulsions which usually have a droplet size less than 100 nm.
How do you make a microemulsion?
Microemulsion systems were prepared by mixing oil with the mixture of surfactant and cosurfactant, and water was added precisely into oily phases with magnetic stirring (300 r/min) at 37°C.
What is oil-in-water nanoemulsion?
Generally, nanoemulsions are oil-in-water emulsions (O/W) as the oil phase is dispersed into the water continuous phase, but can also be water-in-oil emulsions (W/O) when the water phase is dispersed into the oil continuous phase. Nanoemulsions are produced by two main types of processes, low and high energy processes.
What is the size range of microemulsion?
about 10 nm to 300 nm
A microemulsion is a thermodynamically stable fluid. It is different from kinetically stable emulsions which will be break into oil and water over time. The particle size of microemulsions ranges from about 10 nm to 300 nm. Because of the small particle sizes, microemulsions appear as clear or translucent solutions.
What is microemulsion method?
2 Microemulsion methods. A microemulsion is a thermodynamically stable transparent, isotropic dispersion of two immiscible liquids such as water and oil stabilized by surfactant molecules at the water/oil interface.
What is microemulsion and multiple emulsion?
25. These systems are the most studied among the multiple emulsions. The immiscible oil phase, which separates two miscible aqueous phases is known as “liquid membrane” and acts as a different barrier and semi-permeable membrane for the drugs or moieties entrapped in the internal aqueous phase.
What is term microemulsion?
A microemulsion is defined as a thermodynamically stable isotropic dispersion of two immiscible liquids in which the microdomain of either or both liquids was stabilized by an interfacial film of surface-active compounds [42].
What are the advantages of microemulsion?
Microemulsions have been proposed as drug delivery systems to enhance the absorption of drug across biological membranes (Majuru and Oyewumi, 2009). Some of microemulsions advantages include: (1) increased solubility and stability of drugs, and (2) ease and economical scale-up.
What is nanoemulsion technology?
Nanoemulsions are nano-sized emulsions, which are manufactured for improving the delivery of active pharmaceutical ingredients. These are the thermodynamically stable isotropic system in which two immiscible liquids are mixed to form a single phase by means of an emulsifying agent, i.e., surfactant and co-surfactant.
What is the purpose of microemulsion?
Microemulsions have many commercially important uses: Water-in-oil microemulsions for some dry cleaning processes. Floor polishers and cleaners. Personal care products.
What is the difference between a microemulsion and a nanoemulsion?
However, these are distinctly different types of colloidal dispersions: a microemulsion is thermodynamically stable, whereas a nanoemulsion is not.
How stable are microemulsions compared to other emulsions?
basically, microemulsions form spontaneously and are thermodynamically stable. This is not true for nanoemulsions, which are somewhat more stable than common emulsions, but only kinetically stable.
Is it possible to (electron) methods of microemulsion?
a nanoemulsion. It is also possible to have emulsion droplets. Particle shape. Nanoemulsions tend tension. It may therefore be possible to (electron) methods. If a system has non- a microemulsion. On the other hand, if a nanoemulsion. 5. Conclusions and microemulsions. There are many colloidal dispersion being studied. For Microemulsion.
How stable are nanoemulsions in surfactants with Tween 80?
However, relatively stable nanoemulsions and microemulsions could be formed when ≥75 or 50 wt% Tween 80 was incorporated into the surfactant phase, respectively.