What is the most common complication of bone marrow transplantation?

What is the most common complication of bone marrow transplantation?

Bacterial infections are the most common. Viral, fungal and other infections can also occur. Some infections can develop later on, weeks to months after the transplant. Infections can cause extended hospital stay, prevent or delay engraftment, cause organ damage, and may be life threatening.

What is a potential complication following a bone marrow transplant?

Temporary or permanent damage to the liver and heart may be caused by infection, graft-versus-host disease, high doses of chemotherapy and radiation, or fluid overload. Graft failure. Failure of the graft (transplant) taking hold in the marrow is a potential complication.

Can stem cell transplant affect eyesight?

Eye problems usually develop a year after a stem cell transplant, but they can also happen several years later. Eye problems can happen if total body irradiation is given before a stem cell transplant. Chemotherapy and steroids may also increase the chance of developing eye problems.

What is the risk to the recipient from a bone marrow transplant?

A bone marrow transplant has serious risks. Some patients suffer from life-threatening problems as a result of their transplant. These problems can include serious infections and graft-versus-host disease (GVHD) , in which the transplanted cells attack the patient’s body.

What is the average life expectancy after bone marrow transplant?

Some 62% of BMT patients survived at least 365 days, and of those surviving 365 days, 89% survived at least another 365 days. Of the patients who survived 6 years post-BMT, 98.5% survived at least another year.

How long after bone marrow transplant are you immunocompromised?

It usually takes 3 to 12 months for your immune system to recover from your transplant. The first year after transplant is like your first year of life as a newborn baby. During this time, you’re at risk for infection.

What are the side effects of bone marrow test?

Possible risks from bone marrow test

  • Bleeding. It’s not unusual to have a small amount of bleeding from the area where the needle went in.
  • Bruising. Sometimes blood leaks out of the vein and collects under your skin.
  • Infection. There is a small risk of getting an infection in the wound.
  • Pain.
  • Tingling in your leg.

What are the long term side effects of a bone marrow transplant?

Long-term side effects

  • Infertility, meaning you cannot become pregnant or make a woman pregnant when you want to.
  • Cataracts, an eye condition that causes cloudy vision.
  • Sexual side effects and early menopause.
  • Thyroid problems.
  • Lung or bone damage.
  • Another cancer.

What is the life expectancy after a stem cell transplant?

Conditional on surviving the first 2 to 5 years after allogeneic blood or marrow transplantation (BMT), the 10-year overall survival approaches 80%. Nonetheless, the risk of late mortality remains higher than the age- and sex-matched general population for several years after BMT.

Does donating bone marrow shorten your life?

The amount of marrow donated will not weaken your own body or immune system. The average amount of marrow and blood donated is about one quart, less if the patient is a baby or child.

Can you get the Covid vaccine if you had a bone marrow transplant?

Under current guidelines, both solid organ and bone marrow transplant (BMT) recipients are eligible for COVID-19 vaccination. BMT recipients can begin receiving COVID-19 vaccinations three months after transplant, provided the transplanted cells have engrafted or begun growing within bone marrow.

Is bone marrow extraction painful?

With local anesthesia, bone marrow aspiration, in particular, can cause brief, but sharp, pain. Many people choose to also have light sedation for additional pain relief. If you’re anxious about pain, you may be given an IV medication so that you’re either completely or partially sedated during the bone marrow exam.

What are the side effects of bone marrow donation?

About 2.4 percent of donors have a serious complication from anesthesia or damage to bone, nerve, or muscle, according to Be The Match. You’ll only lose a small amount of bone marrow, so it won’t weaken your own immune system. Your body will replace it within six weeks. What are the potential side effects?

What are the risks of bone marrow transplantation?

About 2.4 percent of donors have a serious complication from anesthesia or damage to bone, nerve, or muscle, according to Be The Match. You’ll only lose a small amount of bone marrow, so it won’t weaken your own immune system. Your body will replace it within six weeks.

Do you have to be unconscious to donate bone marrow?

If general anesthesia is used, you will be unconscious during the donation. If you receive regional anesthesia (either spinal or epidural), medication will block sensation in the affected area, but you will remain aware of your surroundings. General anesthesia is used for about 96% of NMDP marrow donors.

What are the side effects of donor donations?

Donors may experience headaches or bone and muscle pain, similar to a cold or the flu, for several days before collection. These are side effects of the filgrastim injections that disappear shortly after donation. Other common side effects are nausea, trouble sleeping and tiredness.