What is the process of assaying?
An assay is a process of analyzing a substance to determine its composition or quality. The term is often used in the mining industry to refer to tests of ore or minerals. The term assay is also used in the environmental, chemical and pharmaceutical industries.
How do you convert anhydrous to as basis?
The assay on anhydrous basis is a mathematically derived value from an experimental results of assay and water content tests. The results of assay and water content tests are determined, separately, on as-is basis. The industry-accepted formula for assay on anhydrous basis = (assay on as-is basis×100)/(100-%water).
How do you calculate potency on a basis?
The formula provided by CLSI to calculate the potency is shown as: Potency = (Assay purity) * (Active fraction) * (1-Water Content).
What is dried basis assay?
Dry basis is an expression of the calculation in chemistry, chemical engineering and related subjects, in which the presence of water (and/or other solvents) is neglected for the purposes of the calculation.
What is assaying in science?
An assay is an investigative (analytic) procedure in laboratory medicine, mining, pharmacology, environmental biology and molecular biology for qualitatively assessing or quantitatively measuring the presence, amount, or functional activity of a target entity.
What is assaying in chemistry?
assaying, in chemical analysis, process of determining proportions of metal, particularly precious metal, in ores and metallurgical products.
What is the difference between anhydrous and dried basis?
Answer: The term ‘dried substance’ takes into account the loss on drying test (including class 3 solvents), whereas ‘anhydrous substance’ refers to the result obtained by water determination.
How is API potency calculated?
Formula to calculate the potency of antibiotic is shown as: Potency = (Assay purity) * (Active fraction) * (1-Water Content).
What is potency formula?
How do you calculate potency on a dry basis?
Difference Between PURITY, ASSAY & POTENCY
- On as is basis = (Area of sample / Area of standard) x (conc. of standard / conc. of sample) x potency or assay of standard.
- On anhydrous basis = (Assay on as is basis / 100 – moisture) x 100.
- On dried basis = (Assay on as is basis / 100 – LOD) x 100.
Is anhydrous same as dry?
As adjectives the difference between anhydrous and dry is that anhydrous is having little or no water while dry is free from liquid or moisture.
What is chemical assaying?
Chemical assays determine the quality of raw materials using quantitative analysis techniques. Organic chemicals and solvents can be assayed using gas chromatography and infrared spectroscopy. Chemical purity is typically determined from the amount of impurities present in a material.
What is a hydrated salt?
If a salt molecule is bound to water molecules, it is a hydrated salt. In another saying, hydrated salt is a salt molecule that is lankly attached to a certain number of water molecules. Most salts are crystals in a hydrated state, meaning that a certain proportion of water is attached to the crystal structure.
What is the general formula for salt hydrate?
Salt hydrates comprise an important group of PCMs. An inorganic salt hydrate (hydrated salt or hydrate) is an ionic compound in which a number of water molecules are attracted by the ions and therefore enclosed within its crystal lattice. The general formula of a hydrated salt is Mx N y. n H 2 O.
How to simulate hydration/dehydration process of salt hydrates at grain level?
Hydration/dehydration processes of salt hydrates at grain level can be described by nucleation and growth reactions. To describe the nucleation process a stochastic model can be used. This stochastic model can be coupled to a deterministic growth model to simulate the conversion process.
What happens when salt hydrates melt?
Salt hydrates usually melt to either a salt hydrate with fewer moles of water, or to its anhydrous form. During the phase change transition, liquid water released from the hydrated salt dissolves the formed nonhydrated salt molecules.