What is trimethoprim and sulfamethoxazole used for?

What is trimethoprim and sulfamethoxazole used for?

Sulfamethoxazole and trimethoprim combination is used to treat infections including urinary tract infections, middle ear infections (otitis media), bronchitis, traveler’s diarrhea, and shigellosis (bacillary dysentery).

What is sulfamethoxazole and trimethoprim 400 mg used for?

This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type).

Is trimethoprim a good antibiotic?

Trimethoprim is an antibiotic. It’s used to treat and prevent urinary tract infections (UTIs), such as cystitis. Occasionally, trimethoprim is used to treat other types of infections, such as chest infections and acne.

What bacteria does sulfamethoxazole trimethoprim treat?


  • infection due to the bacteria Vibrio cholerae.
  • typhoid fever.
  • paratyphoid fever.
  • intestine infection due to the Shigella bacteria.
  • prevention of plague following exposure to plague.
  • infection due to a Brucella bacteria.

Can humans take sulfamethoxazole and trimethoprim?

Adults—800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim once a day. Children 2 months of age and older—Dose is based on body size and must be determined by your doctor.

What are the side effects of trimethoprim-sulfamethoxazole?


  • Black, tarry stools.
  • blistering, peeling, or loosening of the skin.
  • changes in skin color.
  • chest pain or tightness.
  • cough or hoarseness.
  • general feeling of tiredness or weakness.
  • headache.
  • itching, skin rash.

Why is trimethoprim given at night?

To prevent an infection: The dose to prevent infection is half a tablet (150mg) at night. If you have frequent urine infections, you will have to take trimethoprim each night for a few months to prevent recurrent infections. Always take your trimethoprim exactly as your doctor has told you.

What is trimethoprim side effects?

Diarrhea, nausea, vomiting, stomach upset, loss of appetite, changes in taste, and headache may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

What is the strongest antibiotic for a UTI?

What antibiotics can treat a UTI? Not all antibiotics work for treating UTIs, but several do. Trimethoprim/sulfamethoxazole, nitrofurantoin, and fosfomycin are the most preferred antibiotics for treating a UTI.

Is sulfamethoxazole stronger than amoxicillin?

Our results suggest that for acute otitis media twice-daily trimethoprim-sulfamethoxazole is more effective clinically and produces fewer side effects than twice-daily amoxicillin-clavulanate.

Which is a common adverse effect of trimethoprim sulfamethoxazole?

The most common adverse reactions are gastrointestinal disturbances (nausea, vomiting, and anorexia) and allergic skin reactions (such as rash and urticaria). Local reaction, pain and slight irritation on intravenous (IV) administration are infrequent. Thrombophlebitis has been observed.

What are the side effects of trimethoprim sulfamethoxazole?

What is trimethoprim/sulfamethoxazole/SMX?

From Wikipedia, the free encyclopedia Trimethoprim/sulfamethoxazole (TMP/SMX), also known as co-trimoxazole among other names, is an antibiotic used to treat a variety of bacterial infections. It consists of one part trimethoprim to five parts sulfamethoxazole.

Can trimethoprim and sulfamethoxazole be taken together?

Trimethoprim and sulfamethoxazole are commonly used in combination due to possible synergistic effects, and reduced development of resistance. This benefit has been questioned.

Is sulfamethoxazole/trimethoprim/isoniazid/rifampin bactericidal?

“The combination of sulfamethoxazole, trimethoprim, and isoniazid or rifampin is bactericidal and prevents the emergence of drug resistance in Mycobacterium tuberculosis ” (PDF). Antimicrobial Agents and Chemotherapy. 56 (10): 5142–5148. doi: 10.1128/AAC.00832-12. PMC 3457372. PMID 22825115.

What are the side effects of trimethoprim?

Trimethoprim ( TMP) is an antibiotic used mainly in the treatment of bladder infections. Other uses include for middle ear infections and travelers’ diarrhea. With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS. It is taken by mouth. Common side effects include nausea, changes in taste, and rash.