What is ZARXIO prescribed for?

ZARXIO is used to reduce the risk of infection in patients with some tumors who are receiving strong chemotherapy that may cause severe neutropenia with fever.

Is ZARXIO the same as Neupogen?

Zarxio has the same mechanism of action, route of administration, strength, and dosage form as Amgen’s Neupogen.

Is ZARXIO a chemo drug?

What kind of drug is ZARXIO?

ZARXIO is a man-made form of granulocyte colony-stimulating factor (G-CSF) called filgrastim. G-CSF is a natural substance produced by the body. The purpose of G-CSF is to stimulate the growth of neutrophils, a type of white blood cell that is important in the body’s fight against infection.

When should I take zarzio?

The first dose of Zarzio should be administered not less than 24 hours following cytotoxic chemotherapy and within 24 hours of bone marrow or PBPC infusion. Once the neutrophil nadir has been passed, the daily dose of Zarzio should be titrated against the neutrophil response as follows.

What are the side effects of zarzio?

Common side effects of Zarxio include:

fever,
bone and other pain,
rash,
cough,
indigestion,
nosebleed,
headache,
anemia,

Does Zarxio make you tired?

Get medical help right away if you have any very serious side effects, including: breathing problems (such as trouble breathing, fast breathing, shortness of breath), unusual decrease in urination, unusual tiredness, swelling/puffiness of the body. Rarely, serious (possibly fatal) damage to the spleen may occur.

Is Zarxio short-acting?

Zarxio is a short-acting G-CSF biosimilar indicated for2: Patients with cancer receiving myelosuppressive chemotherapy. Patients with acute myeloid leukemia receiving induction or consolidation chemotherapy.

Does ZARXIO make you tired?

How long does it take for ZARXIO to work?

Do not administer ZARXIO within the 24-hour period prior to chemotherapy [see WARNINGS AND PRECAUTIONS]. A transient increase in neutrophil count is typically seen 1 to 2 days after initiation of ZARXIO therapy.

Can ZARXIO be given at home?

ZARXIO may be administered by you, a caregiver, or a healthcare provider. ZARXIO injections can be given by a healthcare provider by subcutaneous (under the skin) injection or by intravenous (IV) injection. Your healthcare provider may decide that subcutaneous injections can be given at home by you or your caregiver.

What do you need to know about Zarxio?

Zarxio 1 FDA Approves Zarxio. The United States Food and Drug Administration (FDA) has approved Zarxio… 2 Patient Information. Read this Patient Information before you start treatment… 3 Zarxio is a man-made form of granulocyte colony-stimulating factor (G-CSF). 4 Zarxio side effects. Spleen rupture. Your spleen may…

Is Zarxio approved by the FDA?

FDA Approves Zarxio. The United States Food and Drug Administration (FDA) has approved Zarxio (filgrastim-sndz), a leukocyte growth factor biosimilar to the reference product Neupogen.

Is Zarxio (filgrastim-sndz) a chemotherapy medication?

No, Zarxio (filgrastim-sndz) is not a chemotherapy medication. People receiving chemotherapy are often prescribed Zarxio (filgrastim-sndz) to raise their white blood cell counts when their levels become too low. Low white blood cells is a common side effect of many chemotherapy medications. Why is Zarxio (filgrastim-sndz) given?

Does Zarxio affect cancer cells?

Potential Effect on Malignant Cells. Zarxio is a growth factor that primarily stimulates neutrophils. The granulocyte colony-stimulating factor (G‑CSF) receptor through which Zarxio acts has also been found on tumor cell lines. The possibility that Zarxio acts as a growth factor for any tumor type cannot be excluded.

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